HRPT2 Antikörper (C-Term)

Produktnummer ABIN2789576

Dieses Anti-HRPT2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HRPT2 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für HRPT2 Antikörper (C-Term) (ABIN2789576)

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRPT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HRPT2 Antikörper

Bindungsspezifität: C-Term

Sequenz: KFVPSDEKKK QGCQRENETL IQRRKDQMQP GGTAISVTVP YRVVDQPLKL

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against CDC73. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 531 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HRPT2

Target: HRPT2 (CDC73) (Parafibromin (CDC73))

Andere Bezeichnung: CDC73

Hintergrund: This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma
Alias Symbols: C1orf28, FLJ23316, HPTJT, HRPT2, HYX
Protein Interaction Partner: CCDC155, FSD2, TSGA10, CEP70, VPS37B, MTUS2, UBC, TFCP2, GOLGA2, ALAS1, CIAO1, AURKB, GPRASP2, COG3, MYH14, MYL12A, ARFGEF2, NUP98, MYH9, CHUK, DNMT3B, DNMT3A, SOX2, BCL9L, PAF1, CTR9, TCF4, CTNNB1, LEO1, GTF2F1, SUV39H1, PTPN11, WDR61, HIST1H3A, RNF20, R
Protein Size: 531

Molekulargewicht: 58 kDa

Gen-ID: 79577

NCBI Accession: NM_024529, NP_078805

UniProt: Q6P1J9

Pathways: Cellular Response to Molecule of Bacterial Origin, Stem Cell Maintenance