IDUA Antikörper (C-Term)

Produktnummer ABIN2789573

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IDUA in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd und Hund.

Kurzübersicht für IDUA Antikörper (C-Term) (ABIN2789573)

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IDUA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-IDUA Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: IDUA Antibody - C-terminal region

Sequenz: DPVAAAPRPL PAGGRLTLRP ALRLPSLLLV HVCARPEKPP GQVTRLRALP

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 86%, Rat: 80%

Produktmerkmale: This is a rabbit polyclonal antibody against IDUA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IDUA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63635-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu IDUA

Target: IDUA (Iduronidase, alpha-L- (IDUA))

Andere Bezeichnung: IDUA

Hintergrund:

Background Information: This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I).

Gene Name: iduronidase, alpha-L-

Alternative Symbols: IDA, MPS1, MPSI

Protein Name: Alpha-L-iduronidase

Molekulargewicht: 73 kDa

Gen-ID: 3425

UniProt: P35475

Pathways: Glycosaminoglycan Metabolic Process