TCP1 alpha/CCTA Antikörper (C-Term)
Kurzübersicht für TCP1 alpha/CCTA Antikörper (C-Term) (ABIN2789568)
Target
Alle TCP1 alpha/CCTA (TCP1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- QAGVFEPTIV KVKSLKFATE AAITILRIDD LIKLHPESKD DKHGSYEDAV
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TCP1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 556 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))
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Andere Bezeichnung
- TCP1
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Hintergrund
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The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.
Alias Symbols: CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha
Protein Interaction Partner: FUS, ERLIN2, HUWE1, CBFA2T2, UBC, TP53, NEDD1, VHL, TUBG1, SUMO2, LGALS3BP, CDC20, STAU1, INPP5K, CDC5L, VRK2, PPP4C, COPA, COPG1, USP9X, PARK2, FBXO6, YWHAQ, UBD, FBXW4, FBXO46, STK25, HDAC6, HDAC3, NPM1, ILK, CDK5, CDK2, PAN2, US3, FAM86B2, CFAP52, METT
Protein Size: 556 -
Molekulargewicht
- 61 kDa
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Gen-ID
- 6950
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NCBI Accession
- NM_030752, NP_110379
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UniProt
- P17987
Target
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