Sclerostin Antikörper (N-Term)
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- Target Alle Sclerostin (SOST) Antikörper anzeigen
- Sclerostin (SOST)
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Kaninchen, Hund, Schwein, Pferd, Rind (Kuh), Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Sclerostin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PELGEYPEPP PELENNKTMN RAENGGRPPH HPFETKDVSE YSCRELHFTR
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SOST. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product SOST Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 213 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Sclerostin (SOST)
- Andere Bezeichnung
- SOST (SOST Produkte)
- Synonyme
- LOC100313724 antikoerper, CDD antikoerper, VBCH antikoerper, 5430411E23Rik antikoerper, sclerostin antikoerper, LOC100313724 antikoerper, SOST antikoerper, Sost antikoerper
- Hintergrund
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Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Alias Symbols: VBCH
Protein Interaction Partner: LRP6, LRP5,
Protein Size: 213 - Molekulargewicht
- 23 kDa
- Gen-ID
- 50964
- NCBI Accession
- NM_025237, NP_079513
- UniProt
- Q9BQB4
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