CCR10 Antikörper (Middle Region)

Produktnummer ABIN2789531

Produktdetails anti-CCR10 Antikörper

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Rind (Kuh), Kaninchen, Schaf, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCR10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ARALPAGPRP STPGRAHLVS VIVWLLSLLL ALPALLFSQD GQREGQRRCR

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 93%, Rat: 86%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CCR10. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 362 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CCR10

Target: CCR10 (Chemokine (C-C Motif) Receptor 10 (CCR10))

Andere Bezeichnung: CCR10 (CCR10 Produkte)

Hintergrund: Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27, CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation.
Alias Symbols: GPR2
Protein Interaction Partner: CCL28, CXCL13, CCL27, CCL25, CCL19, CCR7, CCL7, CCL2, PRRC2A, CCL21,
Protein Size: 362

Molekulargewicht: 40 kDa

Gen-ID: 2826

NCBI Accession: NM_016602, NP_057686

UniProt: P46092