CD207 Antikörper (C-Term)

Produktnummer ABIN2789525

Der Kaninchen Polyklonal anti-CD207 Antikörper (ABIN2789525) detektiert spezifisch CD207 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Meerschweinchen, Pferd, Schwein, Rind (Kuh), Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für CD207 Antikörper (C-Term) (ABIN2789525)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Schwein, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD207 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CD207 Antibody - C-terminal region

Sequenz: GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC

Homologie: Cow: 92%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 83%, Rabbit: 83%, Rat: 83%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CD207. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63502-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: CD207

Hintergrund:

Background Information: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.

Gene Name: CD207 Molecule, langerin

Alternative Symbols: CLEC4K

Protein Name: C-type lectin domain family 4 member K

Molekulargewicht: 36kDa

Gen-ID: 50489

NCBI Accession: NP_056532

UniProt: Q9UJ71