CD207 Antikörper (C-Term)

Produktnummer ABIN2789525

Dieses Anti-CD207-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD207 in WB. Geeignet für Human, Maus, Ratte, Meerschweinchen, Pferd, Schwein, Rind (Kuh), Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für CD207 Antikörper (C-Term) (ABIN2789525)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Schwein, Rind (Kuh), Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD207 Antikörper

Bindungsspezifität: C-Term

Sequenz: GDWSWVDDTP FNKVQSARFW IPGEPNNAGN NEHCGNIKAP SLQAWNDAPC

Homologie: Cow: 92%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 83%, Rabbit: 83%, Rat: 83%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CD207. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 328 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: CD207

Hintergrund: The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity.
Alias Symbols: CLEC4K
Protein Interaction Partner: UBC,
Protein Size: 328

Molekulargewicht: 36 kDa

Gen-ID: 50489

NCBI Accession: NM_015717, NP_056532

UniProt: Q9UJ71