CNR2 Antikörper (C-Term)

Produktnummer ABIN2789519

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-CNR2 Antikörper (ABIN2789519) detektiert spezifisch CNR2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus und Pferd.

Kurzübersicht für CNR2 Antikörper (C-Term) (ABIN2789519)

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Reaktivität: Human, Ratte, Maus, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CNR2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CNR2 Antibody - C-terminal region

Sequenz: MVNPVIYALR SGEIRSSAHH CLAHWKKCVR GLGSEAKEEA PRSSVTETEA

Homologie: Horse: 83%, Human: 100%, Mouse: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against CNR2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63486-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CNR2 Antikörper (ABIN2789519)

Wilhelmsen, Khakpour, Tran, Sheehan, Schumacher, Xu, Hellman: "The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells." in: The Journal of biological chemistry, Vol. 289, Issue 19, pp. 13079-100, (2014) (PubMed).

Details zu CNR2

Target: CNR2 (Cannabinoid Receptor 2 (CNR2))

Andere Bezeichnung: CNR2

Hintergrund:

Background Information: The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.

Gene Name: Cannabinoid receptor 2 (macrophage)

Alternative Symbols: CB2, CX5, CB-2

Protein Name: Cannabinoid receptor 2

Molekulargewicht: 40kDa

Gen-ID: 1269

NCBI Accession: NP_001832

UniProt: P34972