Translin Antikörper (Middle Region)
Kurzübersicht für Translin Antikörper (Middle Region) (ABIN2789513)
Target
Alle Translin (TSN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- LVTREAVTEI LGIEPDREKG FHLDVEDYLS GVLILASELS RLSVNSVTAG
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
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Produktmerkmale
- This is a rabbit polyclonal antibody against TSN. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 228 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Translin (TSN)
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Andere Bezeichnung
- TSN
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Hintergrund
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This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms.
Alias Symbols: BCLF-1, RCHF1, REHF-1, TBRBP, TRSLN
Protein Interaction Partner: UBC, WDR12, NSUN2, TSNAX, TBCD, SHMT1, PPP3CA, PFDN1, NRD1, ETF1, ATP6V1C1, SETSIP, FAM129B, P3H1, ELAC2, SNX6, MYC, GIT2, TSN, EIF4A3, MAGOH, UBA6, VPS29, UCHL3, TTC4, ZBTB18, PPP1R15A, HCVgp1,
Protein Size: 228 -
Molekulargewicht
- 25 kDa
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Gen-ID
- 7247
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NCBI Accession
- NM_004622, NP_004613
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UniProt
- Q15631
Target
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