CD1e Antikörper (C-Term)
Kurzübersicht für CD1e Antikörper (C-Term) (ABIN2789492)
Target
Alle CD1e Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- WVMWMRGEQE QRGTQRGDVL PNADETWWIF HLSHPDLFDC DSYPGHIGCS
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 79%, Pig: 86%, Rat: 79%, Sheep: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CD1E. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD1E
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeat freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD1e
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Andere Bezeichnung
- CD1E
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Hintergrund
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This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found, however, their biological validity has not been determined.
Protein Interaction Partner: UBC, B2M,
Protein Size: 290 -
Molekulargewicht
- 31 kDa
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Gen-ID
- 913
Target
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