DGAT1 Antikörper (N-Term)

Produktnummer ABIN2789488

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch DGAT1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Schwein, Schaf, Ziege, Kaninchen, Pferd, Meerschweinchen und Zebrafisch (Danio rerio).

Kurzübersicht für DGAT1 Antikörper (N-Term) (ABIN2789488)

Target: DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Schwein, Schaf, Ziege, Kaninchen, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DGAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DGAT1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Dgat1 Antibody - N-terminal region

Sequenz: HRLQDSLFSS DSGFSNYRGI LNWCVVMLIL SNARLFLENL IKYGILVDPI

Homologie: Cow: 100%, Dog: 93%, Goat: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against Dgat1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Dgat1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63409-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DGAT1

Target: DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))

Andere Bezeichnung: Dgat1

Hintergrund:

Background Information: Dgat1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. It may be involved in VLDL (very low density lipoprotein) assembly. In liver, Dgat1 plays a role in esterifying exogenous fatty acids to glycerol. It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.

Gene Name: diacylglycerol O-acyltransferase 1

Alternative Symbols: ARAT, Dgat, C75990, D15Ertd23, D15Ertd23e

Protein Name: Diacylglycerol O-acyltransferase 1

Molekulargewicht: 57kDa

Gen-ID: 13350

NCBI Accession: NP_034176

UniProt: Q9Z2A7

Pathways: Hormone Transport