SMN1 Antikörper (C-Term)

Produktnummer ABIN2789460

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SMN1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Schwein, Kaninchen, Meerschweinchen, Pferd und Rind (Kuh).

Kurzübersicht für SMN1 Antikörper (C-Term) (ABIN2789460)

Target: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMN1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: SMN1 Antibody - C-terminal region

Sequenz: PPPPPICPDS LDDADALGSM LISWYMSGYH TGYYMGFRQN QKEGRCSHSL

Homologie: Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 85%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SMN1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of SMN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63347-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SMN1

Target: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Andere Bezeichnung: SMN1

Hintergrund:

Background Information: SMN1 localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein.

Alternative Symbols: SMA, SMN, SMA1, SMA2, SMA3, SMA4, SMA@, SMNT, BCD541, GEMIN1, TDRD16A, T-BCD541

Protein Name: Survival motor neuron protein

Molekulargewicht: 28kDa

Gen-ID: 6606

NCBI Accession: NP_075012

UniProt: Q16637

Pathways: Ribonucleoprotein Complex Subunit Organization