SMN1 Antikörper (C-Term)

Produktnummer ABIN2789460

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMN1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Schwein, Kaninchen, Meerschweinchen, Pferd und Rind (Kuh).

Kurzübersicht für SMN1 Antikörper (C-Term) (ABIN2789460)

Target: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Reaktivität: Human, Maus, Ratte, Hund, Schwein, Kaninchen, Meerschweinchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMN1 Antikörper

Bindungsspezifität: C-Term

Sequenz: PPPPPICPDS LDDADALGSM LISWYMSGYH TGYYMGFRQN QKEGRCSHSL

Homologie: Cow: 77%, Dog: 92%, Guinea Pig: 92%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 100%, Rabbit: 85%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SMN1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of SMN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 262 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMN1

Target: SMN1 (Survival of Motor Neuron 1, Telomeric (SMN1))

Andere Bezeichnung: SMN1

Hintergrund: SMN1 localizes to both the cytoplasm and the nucleus. Within the nucleus, the protein localizes to subnuclear bodies called gems which are found near coiled bodies containing high concentrations of small ribonucleoproteins (snRNPs). This protein forms heteromeric complexes with proteins such as SIP1 and GEMIN4, and also interacts with several proteins known to be involved in the biogenesis of snRNPs, such as hnRNP U protein and the small nucleolar RNA binding protein.
Alias Symbols: BCD541, SMA, SMA1, SMA2, SMA3, SMA4, SMA@, SMN, SMN2, SMNT, T-BCD541
Protein Interaction Partner: COPA, RNF2, BMI1, KDM1A, SMN1, RN7SL1, UBC, HDAC11, MIB1, GEMIN4, DICER1, DDX20, PAN2, RBFOX2, HNRNPUL1, IQCB1, UBL4A, SMN2, NOS2, vpr, GEMIN2, SRP68, SRP54, SRP19, SRP9, RNU2-1, RNU1-1, GEMIN5, MDC1, RBM25, COIL, SRSF5, HSPB1, CUL3, DDAH2, MAST2, SMC5, R
Protein Size: 262

Molekulargewicht: 28 kDa

Gen-ID: 6606

NCBI Accession: NM_022874, NP_075012

Pathways: Ribonucleoprotein Complex Subunit Organization