ARHGEF1 Antikörper (N-Term)

Produktnummer ABIN2789444

Der Kaninchen Polyklonal anti-ARHGEF1 Antikörper (ABIN2789444) detektiert spezifisch ARHGEF1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Pferd und Schwein.

Kurzübersicht für ARHGEF1 Antikörper (N-Term) (ABIN2789444)

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARHGEF1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ARHGEF1 Antibody - N-terminal region

Sequenz: SAAVVNAIGL YMRHLGVRTK SGDKKSGRNF FRKKVMGNRR SDEPAKTKKG

Homologie: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARHGEF1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHGEF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63316-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ARHGEF1

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Andere Bezeichnung: ARHGEF1

Hintergrund:

Background Information: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Gene Name: Rho guanine nucleotide exchange factor (GEF) 1

Alternative Symbols: LSC, GEF1, IMD62, LBCL2, SUB1.5, P115-RHOGEF

Protein Name: Rho guanine nucleotide exchange factor 1

Molekulargewicht: 102kDa

Gen-ID: 9138

NCBI Accession: NP_945353

UniProt: Q92888

Pathways: Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling