ARHGEF1 Antikörper (N-Term)

Produktnummer ABIN2789444

Der Kaninchen Polyklonal anti-ARHGEF1 Antikörper (ABIN2789444) detektiert spezifisch ARHGEF1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Pferd und Schwein.

Kurzübersicht für ARHGEF1 Antikörper (N-Term) (ABIN2789444)

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARHGEF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARHGEF1 Antikörper

Bindungsspezifität: N-Term

Sequenz: SAAVVNAIGL YMRHLGVRTK SGDKKSGRNF FRKKVMGNRR SDEPAKTKKG

Homologie: Cow: 93%, Dog: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ARHGEF1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ARHGEF1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 912 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARHGEF1

Target: ARHGEF1 (rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1))

Andere Bezeichnung: ARHGEF1

Hintergrund: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.
Alias Symbols: GEF1, LBCL2, LSC, P115-RHOGEF, SUB1.5
Protein Interaction Partner: TCF4, UBC, CYFIP1, CAP2, FN1, DCUN1D1, SH3KBP1, CSNK1E, SREBF2, MEPCE, TAF10, CNKSR1, GNA13, ARHGEF1, PRKCA, CD44, RAP1A, HRAS, PIK3CA, RHOA, GNA12, ATR,
Protein Size: 912

Molekulargewicht: 102 kDa

Gen-ID: 9138

NCBI Accession: NM_199002, NP_945353

UniProt: Q92888

Pathways: Neurotrophin Signalübertragung, Regulation of G-Protein Coupled Receptor Protein Signaling, Thromboxane A2 Receptor Signaling