PIN1 Antikörper (N-Term)

Produktnummer ABIN2789425

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PIN1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für PIN1 Antikörper (N-Term) (ABIN2789425)

Target: PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIN1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PIN1 Antikörper

Bindungsspezifität: N-Term

Sequenz: RPSGNSSSGG KNGQGEPARV RCSHLLVKHS QSRRPSSWRQ EKITRTKEEA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PIN1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 163 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PIN1

Target: PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))

Andere Bezeichnung: PIN1

Hintergrund: Peptidyl-prolyl cis/trans isomerases (PPIases) catalyze the cis/trans isomerization of peptidyl-prolyl peptide bonds. This gene encodes one of the PPIases, which specifically binds to phosphorylated ser/thr-pro motifs to catalytically regulate the post-phosphorylation conformation of its substrates. The conformational regulation catalyzed by this PPIase has a profound impact on key proteins involved in the regulation of cell growth, genotoxic and other stress responses, the immune response, induction and maintenance of pluripotency, germ cell development, neuronal differentiation, and survival. This enzyme also plays a key role in the pathogenesis of Alzheimer's disease and many cancers. Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: DOD, UBL5
Protein Interaction Partner: ANKRD40, KRTAP4-2, ZMIZ2, TSC22D4, THAP7, CCDC33, CEP76, HOMEZ, ZNF446, FBXW7, CEP55, ADAMTSL4, ZBTB7B, SSBP3, NUP62, MTUS2, ARHGEF15, IKZF3, RBPMS, RAI1, CCDC184, KRTAP10-3, KRTAP10-1, KRTAP10-9, KRTAP10-7, TAB3, ZBTB9, SPERT, AMOT, PRRC1, KRT40, HEXIM2,
Protein Size: 163

Molekulargewicht: 18 kDa

Gen-ID: 5300

NCBI Accession: NM_006221, NP_006212

UniProt: Q13526