DRD3 Antikörper (C-Term)

Produktnummer ABIN2789395

Der Kaninchen Polyklonal anti-DRD3 Antikörper wird verwendet zum Nachweis von DRD3 in Proben von Human, Ratte, Hund, Pferd, Schwein, Rind (Kuh) und Meerschweinchen. Er wurde validiert für WB.

Kurzübersicht für DRD3 Antikörper (C-Term) (ABIN2789395)

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Reaktivität: Human, Ratte, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DRD3 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: DRD3 Antibody - C-terminal region

Sequenz: QERGGELKRE EKTRNSLMPL REKKATQMVA IVLGAFIVCW LPFFLTHVLN

Homologie: Cow: 77%, Dog: 86%, Guinea Pig: 75%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DRD3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63162-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Andere Bezeichnung: DRD3

Hintergrund:

Background Information: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).

Gene Name: Dopamine receptor D3

Alternative Symbols: D3DR, ETM1, FET1

Protein Name: D(3) dopamine receptor

Molekulargewicht: 41kDa

Gen-ID: 1814

NCBI Accession: NP_387512

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity