DRD3 Antikörper (C-Term)

Produktnummer ABIN2789395

Der Kaninchen Polyklonal Anti-DRD3-Antikörper wurde für WB validiert. Er ist geeignet, DRD3 in Proben von Human, Ratte, Hund, Pferd, Schwein, Rind (Kuh) und Meerschweinchen zu detektieren.

Kurzübersicht für DRD3 Antikörper (C-Term) (ABIN2789395)

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Reaktivität: Human, Ratte, Hund, Pferd, Schwein, Rind (Kuh), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DRD3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DRD3 Antikörper

Bindungsspezifität: C-Term

Sequenz: QERGGELKRE EKTRNSLMPL REKKATQMVA IVLGAFIVCW LPFFLTHVLN

Homologie: Cow: 77%, Dog: 86%, Guinea Pig: 75%, Horse: 79%, Human: 100%, Pig: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against DRD3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 367 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DRD3

Target: DRD3 (Dopamine Receptor D3 (DRD3))

Andere Bezeichnung: DRD3

Hintergrund: This gene encodes the D3 subtype of the five (D1-D5) dopamine receptors. The activity of the D3 subtype receptor is mediated by G proteins which inhibit adenylyl cyclase. This receptor is localized to the limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. Genetic variation in this gene may be associated with susceptibility to hereditary essential tremor 1. Alternative splicing of this gene results in transcript variants encoding different isoforms, although some variants may be subject to nonsense-mediated decay (NMD).
Alias Symbols: D3DR, ETM1, FET1, MGC149204, MGC149205
Protein Interaction Partner: SLC9A3, USP48, EEF1G, CLIC6, MPDZ, EPB41L2, GIPC1, NCS1, EPB41L1, EEF1B2, NCK1, FLNA, GNAI1, EPB41, GRB2, RDX,
Protein Size: 367

Molekulargewicht: 41 kDa

Gen-ID: 1814

NCBI Accession: NM_033663, NP_387512

UniProt: P35462

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Proton Transport, Negative Regulation of Transporter Activity