L1CAM Antikörper (C-Term)

Produktnummer ABIN2789372

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch L1CAM in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd und Rind (Kuh).

Kurzübersicht für L1CAM Antikörper (C-Term) (ABIN2789372)

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Kaninchen, Meerschweinchen, Pferd, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser L1CAM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-L1CAM Antikörper

Bindungsspezifität: C-Term

Sequenz: GDIKPLGSDD SLADYGGSVD VQFNEDGSFI GQYSGKKEKE AAGGNDSSGA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against L1CAM. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1257 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu L1CAM

Target: L1CAM (L1 Cell Adhesion Molecule (L1CAM))

Andere Bezeichnung: L1CAM

Hintergrund: The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant.
Alias Symbols: CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAML1, S10, SPG1, NCAM-L1, N-CAM-L1
Protein Interaction Partner: RANBP9, FBXO6, NRP1, Caskin1, RABGEF1, UBC, EZR, CANX, CNTN1, NUMB, PEA15, RPS6KA2, RPS6KA1, NCAN, MSN, ITGAV, CNTN2, ANK1, RDX, PRNP, ITGA5, NCAM1, CSNK2A1, ANK2, AP2A1, AP2M1,
Protein Size: 1257

Molekulargewicht: 138 kDa

Gen-ID: 3897

NCBI Accession: NM_000425, NP_000416

UniProt: P32004

Pathways: Synaptic Membrane