BMP4 Antikörper (C-Term)

Produktnummer ABIN2789354

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-BMP4 Antikörper (ABIN2789354) detektiert spezifisch BMP4 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Kaninchen, Schwein, Rind (Kuh), Hund, Ziege, Schaf, Meerschweinchen und Pferd.

Kurzübersicht für BMP4 Antikörper (C-Term) (ABIN2789354)

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reaktivität: Human, Ratte, Maus, Kaninchen, Schwein, Rind (Kuh), Hund, Ziege, Schaf, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BMP4 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: BMP4 Antibody - C-terminal region

Sequenz: NWAQLRPLLV TFGHDGRGHA LTRRRRAKRS PKHHSQRARK KNKNCRRHSL

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against BMP4. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63062-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-BMP4 Antikörper (ABIN2789354)

Ganti, Hunt, Parapuram, Hunt: "Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells." in: Investigative ophthalmology & visual science, Vol. 48, Issue 4, pp. 1853-63, (2007) (PubMed).

Details zu BMP4

Target: BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Andere Bezeichnung: BMP4

Hintergrund:

Background Information: The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Gene Name: Bone morphogenetic protein 4

Alternative Symbols: ZYME, BMP2B, OFC11, BMP2B1, MCOPS6

Protein Name: Bone morphogenetic protein 4

Molekulargewicht: 40 kDa

Gen-ID: 652

NCBI Accession: NP_001193

UniProt: P12644

Pathways: Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development