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BMP4 Antikörper (C-Term)

Dieses Anti-BMP4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BMP4 in WB. Geeignet für Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Schaf, Hund, Ziege, Meerschweinchen und Pferd. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN2789354

Kurzübersicht für BMP4 Antikörper (C-Term) (ABIN2789354)

Target

Alle BMP4 Antikörper anzeigen
BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reaktivität

  • 72
  • 44
  • 39
  • 19
  • 15
  • 12
  • 8
  • 8
  • 6
  • 5
  • 5
  • 2
  • 2
  • 2
  • 1
Human, Ratte, Maus, Schwein, Kaninchen, Rind (Kuh), Schaf, Hund, Ziege, Meerschweinchen, Pferd

Wirt

  • 120
  • 25
  • 11
  • 1
  • 1
Kaninchen

Klonalität

  • 128
  • 30
Polyklonal

Konjugat

  • 87
  • 27
  • 13
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BMP4 Antikörper ist unkonjugiert

Applikation

  • 136
  • 78
  • 58
  • 42
  • 40
  • 14
  • 14
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 12
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Sequenz

    NWAQLRPLLV TFGHDGRGHA LTRRRRAKRS PKHHSQRARK KNKNCRRHSL

    Homologie

    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against BMP4. It was validated on Western Blot.

    Aufreinigung

    Affinity Purified
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 408 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Ganti, Hunt, Parapuram, Hunt: "Vitreous modulation of gene expression in low-passage human retinal pigment epithelial cells." in: Investigative ophthalmology & visual science, Vol. 48, Issue 4, pp. 1853-63, (2007) (PubMed).

  • Target

    BMP4 (Bone Morphogenetic Protein 4 (BMP4))

    Andere Bezeichnung

    BMP4

    Hintergrund

    The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.
    Alias Symbols: BMP2B, BMP2B1, MCOPS6, OFC11, ZYME
    Protein Interaction Partner: BMPR2, ZFYVE9, UBC, BGN, GREM2, BMPER, SOSTDC1, CHRDL2, STAP2, BMPR1B, NOG, BMP8B, HTRA1, BMPR1A, CHRDL1, BMP4, TWSG1, CHRD,
    Protein Size: 408

    Molekulargewicht

    46 kDa

    Gen-ID

    652

    NCBI Accession

    NM_001202, NP_001193

    UniProt

    P12644

    Pathways

    Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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