ALOX5 Antikörper (C-Term)

Produktnummer ABIN2789351

Der Kaninchen Polyklonal Anti-ALOX5-Antikörper wurde für WB validiert. Er ist geeignet, ALOX5 in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd und Meerschweinchen zu detektieren.

Kurzübersicht für ALOX5 Antikörper (C-Term) (ABIN2789351)

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALOX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ALOX5 Antikörper

Bindungsspezifität: C-Term

Sequenz: FGQLFLGMYP EEHFIEKPVK EAMARFRKNL EAIVSVIAER NKKKQLPYYY

Homologie: Cow: 86%, Dog: 79%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ALOX5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human ALOX5

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ALOX5

Target: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Andere Bezeichnung: ALOX5

Hintergrund: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: CEP57L1, NUTM1, SYCE1, CEP63, HHIPL2, COTL1, MAD1L1, REL, MEOX1, PIK3R1, DICER1, MAPKAPK2, LTC4S, ALOX5AP, APP, TGFBRAP1, GRB2, ACTB,
Protein Size: 617

Molekulargewicht: 67 kDa

Gen-ID: 240

NCBI Accession: NP_001243083

UniProt: B7ZLS0