CD1a Antikörper (C-Term)

Produktnummer ABIN2789348

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD1a in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Hund, Ratte, Schwein, Rind (Kuh), Meerschweinchen, Pferd und Schaf.

Kurzübersicht für CD1a Antikörper (C-Term) (ABIN2789348)

Target: CD1a

Reaktivität: Human, Maus, Hund, Ratte, Schwein, Rind (Kuh), Meerschweinchen, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD1a Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD1a Antikörper

Bindungsspezifität: C-Term

Sequenz: KPEAWLSHGP SPGPGHLQLV CHVSGFYPKP VWVMWMRGEQ EQQGTQRGDI

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rat: 79%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CD1A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 327 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD1a

Target: CD1a

Andere Bezeichnung: CD1A

Hintergrund: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.
Alias Symbols: CD1, FCB6, HTA1, R4, T6
Protein Interaction Partner: UBTD1, KCTD5, DGAT1, VWA5A, B2M,
Protein Size: 327

Molekulargewicht: 37 kDa

Gen-ID: 909

NCBI Accession: NM_001763, NP_001754

UniProt: P06126

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process