CD68 Antikörper (N-Term)

Produktnummer ABIN2789336

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CD68 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Rind (Kuh) und Pferd.

Kurzübersicht für CD68 Antikörper (N-Term) (ABIN2789336)

Target: CD68 (CD68 Molecule (CD68))

Reaktivität: Human, Rind (Kuh), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD68 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD68 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: CD68 Antibody - N-terminal region

Sequenz: LLAAQGTGND CPHKKSATLL PSFTVTPTVT ESTGTTSHRT TKSHKTTTHR

Homologie: Cow: 93%, Horse: 79%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CD68. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63009-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu CD68

Target: CD68 (CD68 Molecule (CD68))

Andere Bezeichnung: CD68

Hintergrund:

Background Information: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages.

Gene Name: CD68 Molecule

Alternative Symbols: GP110, LAMP4, SCARD1

Protein Name: Macrosialin

Molekulargewicht: 37kDa

Gen-ID: 968

NCBI Accession: NP_001242

UniProt: P34810