CD68 Antikörper (Middle Region)

Produktnummer ABIN2789335

Dieses Anti-CD68-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD68 in WB. Geeignet für Human, Maus, Ratte, Meerschweinchen und Schwein.

Kurzübersicht für CD68 Antikörper (Middle Region) (ABIN2789335)

Target: CD68 (CD68 Molecule (CD68))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD68 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CD68 Antikörper

Bindungsspezifität: Middle Region

Sequenz: EAWGISVLNP NKTKVQGSCE GAHPHLLLSF PYGHLSFGFM QDLQQKVVYL

Homologie: Guinea Pig: 79%, Human: 100%, Mouse: 79%, Pig: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CD68. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 327 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CD68

Target: CD68 (CD68 Molecule (CD68))

Andere Bezeichnung: CD68

Hintergrund: This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages.
Alias Symbols: DKFZp686M18236, GP110, SCARD1, LAMP4
Protein Interaction Partner: ADRB2, RALGDS,
Protein Size: 327

Molekulargewicht: 35 kDa

Gen-ID: 968

NCBI Accession: NM_001040059, NP_001035148

UniProt: B4DVT4