AVPR1B Antikörper (C-Term)

Produktnummer ABIN2789328

Der Kaninchen Polyklonal Anti-AVPR1B Antikörper wurde für WB validiert. Er ist geeignet, AVPR1B in Proben von Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Schaf zu detektieren.

Kurzübersicht für AVPR1B Antikörper (C-Term) (ABIN2789328)

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AVPR1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AVPR1B Antikörper

Bindungsspezifität: C-Term

Sequenz: TISRAKIRTV KMTFVIVLAY IACWAPFFSV QMWSVWDKNA PDEDSTNVAF

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against AVPR1B. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 424 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AVPR1B

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Andere Bezeichnung: AVPR1B

Hintergrund: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
Alias Symbols: AVPR3
Protein Interaction Partner: GRK5, AVP, PRKCA,
Protein Size: 424

Molekulargewicht: 47 kDa

Gen-ID: 553

NCBI Accession: NM_000707, NP_000698

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones