AVPR1B Antikörper (C-Term)
Kurzübersicht für AVPR1B Antikörper (C-Term) (ABIN2789328)
Target
Alle AVPR1B Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- TISRAKIRTV KMTFVIVLAY IACWAPFFSV QMWSVWDKNA PDEDSTNVAF
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 75%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%, Sheep: 93%
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Produktmerkmale
- This is a rabbit polyclonal antibody against AVPR1B. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 424 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))
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Andere Bezeichnung
- AVPR1B
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Hintergrund
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The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
Alias Symbols: AVPR3
Protein Interaction Partner: GRK5, AVP, PRKCA,
Protein Size: 424 -
Molekulargewicht
- 47 kDa
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Gen-ID
- 553
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NCBI Accession
- NM_000707, NP_000698
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UniProt
- P47901
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Pathways
- Regulation of Systemic Arterial Blood Pressure by Hormones
Target
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