SIK2 Antikörper (N-Term)

Produktnummer ABIN2789222

Produktdetails anti-SIK2 Antikörper

Target: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VLYPQEQENE PSIGEFNEQV LRLMHSLGID QQKTIESLQN KSYNHFAAIY

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SIK2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 926 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SIK2

Target: SIK2 (Salt-Inducible Kinase 2 (SIK2))

Andere Bezeichnung: SIK2 (SIK2 Produkte)

Synonyme: PIG33 antikoerper, SC1 antikoerper, LOH11CR1I antikoerper, QIK antikoerper, SNF1LK2 antikoerper, G630080D20Rik antikoerper, Snf1lk2 antikoerper, RGD1559698 antikoerper, si:dkey-27p23.1 antikoerper, snf1lk2a antikoerper, SPARC like 1 antikoerper, salt inducible kinase 2 antikoerper, salt-inducible kinase 2 antikoerper, salt-inducible kinase 2a antikoerper, SPARCL1 antikoerper, SIK2 antikoerper, SLK2 antikoerper, Sik2 antikoerper, sik2a antikoerper

Hintergrund: SIK2 phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. It inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Alias Symbols: DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2
Protein Interaction Partner: GABARAPL2, YWHAZ, YWHAE, VCP, HSPA4, HDAC5, CEP250, UBC, APP, BMH1, CRTC2, YWHAQ, PRKAA1, IRS1,
Protein Size: 926

Molekulargewicht: 102 kDa

Gen-ID: 23235

NCBI Accession: NM_015191, NP_056006

UniProt: Q9H0K1