SIK2 Antikörper (N-Term)
Kurzübersicht für SIK2 Antikörper (N-Term) (ABIN2789222)
Target
Alle SIK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- N-Term
-
Sequenz
- VLYPQEQENE PSIGEFNEQV LRLMHSLGID QQKTIESLQN KSYNHFAAIY
-
Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against SIK2. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 926 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- SIK2 (Salt-Inducible Kinase 2 (SIK2))
-
Andere Bezeichnung
- SIK2
-
Hintergrund
-
SIK2 phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. It inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Alias Symbols: DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2
Protein Interaction Partner: GABARAPL2, YWHAZ, YWHAE, VCP, HSPA4, HDAC5, CEP250, UBC, APP, BMH1, CRTC2, YWHAQ, PRKAA1, IRS1,
Protein Size: 926 -
Molekulargewicht
- 102 kDa
-
Gen-ID
- 23235
-
NCBI Accession
- NM_015191, NP_056006
-
UniProt
- Q9H0K1
Target
-