SIK2 Antikörper (N-Term)
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- Target Alle SIK2 Antikörper anzeigen
- SIK2 (Salt-Inducible Kinase 2 (SIK2))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Kaninchen, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SIK2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- VLYPQEQENE PSIGEFNEQV LRLMHSLGID QQKTIESLQN KSYNHFAAIY
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SIK2. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Top Product
- Discover our top product SIK2 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 926 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SIK2 (Salt-Inducible Kinase 2 (SIK2))
- Andere Bezeichnung
- SIK2 (SIK2 Produkte)
- Hintergrund
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SIK2 phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. It inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Alias Symbols: DKFZp434K1115, KIAA0781, LOH11CR1I, QIK, SNF1LK2
Protein Interaction Partner: GABARAPL2, YWHAZ, YWHAE, VCP, HSPA4, HDAC5, CEP250, UBC, APP, BMH1, CRTC2, YWHAQ, PRKAA1, IRS1,
Protein Size: 926 - Molekulargewicht
- 102 kDa
- Gen-ID
- 23235
- NCBI Accession
- NM_015191, NP_056006
- UniProt
- Q9H0K1
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