MRPS31 Antikörper (N-Term)

Produktnummer ABIN2789214

Produktdetails anti-MRPS31 Antikörper

Target: MRPS31 (Mitochondrial Ribosomal Protein S31 (MRPS31))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MRPS31 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LTVRHGTVRY RSSALLARTK NNIQRYFGTN SVICSKKDKQ SVRTEETSKE

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MRPS31. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 395 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MRPS31

Target: MRPS31 (Mitochondrial Ribosomal Protein S31 (MRPS31))

Andere Bezeichnung: MRPS31 (MRPS31 Produkte)

Hintergrund: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes, however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
Alias Symbols: IMOGN38, MRP-S31, S31mt
Protein Interaction Partner: GRSF1, UBC, SMURF2, PARK2, STAT3, ESR2, SARNP, CPSF7, SRPRB, FLOT1, CUL3, ICT1, USP42, EIF6, LYST,
Protein Size: 395

Molekulargewicht: 43 kDa

Gen-ID: 10240

NCBI Accession: NM_005830, NP_005821

UniProt: Q92665