EEF1E1 Antikörper (N-Term)

Produktnummer ABIN2789165

Produktdetails anti-EEF1E1 Antikörper

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEF1E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IPVLQTNNGP SLTGLTTIAA HLVKQANKEY LLGSTAEEKA IVQQWLEYRV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EEF1E1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 174 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EEF1E1

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Andere Bezeichnung: EEF1E1 (EEF1E1 Produkte)

Hintergrund: This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
Alias Symbols: AIMP3, P18
Protein Interaction Partner: NAT9, CALCOCO2, HUWE1, RPLP0, RPL27A, RPL26, RPL24, RPL23A, RPL21, RPL18, RPL15, RPL13, RPL7A, QARS, MARS, CCAR2, RPL36, AIMP1, IQGAP1, AIMP2, IARS, DNAJA1, HNRNPA2B1, EIF4G1, EIF2S3, EIF2S1, DARS, gag, UBC, ITGA4, RARS, KARS, EPRS, ATR, ATM,
Protein Size: 174

Molekulargewicht: 19 kDa

Gen-ID: 9521

NCBI Accession: NM_004280, NP_004271

UniProt: O43324

Pathways: Positive Regulation of Response to DNA Damage Stimulus