EEF1E1 Antikörper (N-Term)

Produktnummer ABIN2789165

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch EEF1E1 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Hund.

Kurzübersicht für EEF1E1 Antikörper (N-Term) (ABIN2789165)

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EEF1E1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EEF1E1 Antikörper

Bindungsspezifität: N-Term

Sequenz: IPVLQTNNGP SLTGLTTIAA HLVKQANKEY LLGSTAEEKA IVQQWLEYRV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EEF1E1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 174 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EEF1E1

Target: EEF1E1 (Eukaryotic Translation Elongation Factor 1 epsilon 1 (EEF1E1))

Andere Bezeichnung: EEF1E1

Hintergrund: This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2.
Alias Symbols: AIMP3, P18
Protein Interaction Partner: NAT9, CALCOCO2, HUWE1, RPLP0, RPL27A, RPL26, RPL24, RPL23A, RPL21, RPL18, RPL15, RPL13, RPL7A, QARS, MARS, CCAR2, RPL36, AIMP1, IQGAP1, AIMP2, IARS, DNAJA1, HNRNPA2B1, EIF4G1, EIF2S3, EIF2S1, DARS, gag, UBC, ITGA4, RARS, KARS, EPRS, ATR, ATM,
Protein Size: 174

Molekulargewicht: 19 kDa

Gen-ID: 9521

NCBI Accession: NM_004280, NP_004271

UniProt: O43324

Pathways: Positive Regulation of Response to DNA Damage Stimulus