TSEN2 Antikörper (C-Term)

Produktnummer ABIN2789135

Produktdetails anti-TSEN2 Antikörper

Target: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Bindungsspezifität: C-Term

Reaktivität: Human, Hund, Pferd, Kaninchen, Rind (Kuh), Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSEN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LRRPLSWKSL AALSRVSVNV SKELMLCYLI KPSTMTDKEM ESPECMKRIK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 79%, Horse: 100%, Human: 100%, Pig: 93%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against TSEN2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 465 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TSEN2

Target: TSEN2 (tRNA-splicing Endonuclease Subunit SEN2 (TSEN2))

Andere Bezeichnung: TSEN2 (TSEN2 Produkte)

Hintergrund: This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: MGC2776, MGC4440, PCH2B, SEN2, SEN2L
Protein Interaction Partner: TSEN54, UBC, TBC1D2, PRPF39, POLD3, TBC1D4, TRIP10, USP8, POLD1, Clp1, RANBP10, TSEN15, TSEN34,
Protein Size: 465

Molekulargewicht: 51 kDa

Gen-ID: 80746

NCBI Accession: NM_025265, NP_079541

UniProt: Q8NCE0

Pathways: Nuclear Receptor Transcription Pathway, Regulation of Lipid Metabolism by PPARalpha