C16orf57 Antikörper (C-Term)

Produktnummer ABIN2789122

Der Kaninchen Polyklonal anti-C16orf57 Antikörper (ABIN2789122) detektiert spezifisch C16orf57 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Zebrafisch (Danio rerio).

Kurzübersicht für C16orf57 Antikörper (C-Term) (ABIN2789122)

Target: C16orf57 (USB1) (U6 SnRNA Biogenesis 1 (USB1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser C16orf57 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-C16orf57 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: C16orf57 Antibody - C-terminal region

Sequenz: RFFFTANQVK IYTNQEKTRT FIGLEVTSGH AQFLDLVSEV DRVMEEFNLT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against C16orf57. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62380-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu C16orf57

Target: C16orf57 (USB1) (U6 SnRNA Biogenesis 1 (USB1))

Andere Bezeichnung: C16orf57

Hintergrund:

Background Information: This gene encodes a protein with several conserved domains, however, its exact function is not known. Mutations in this gene are associated with poikiloderma with neutropenia (PN), which shows phenotypic overlap with Rothmund-Thomson syndrome (RTS) caused by mutations in the RECQL4 gene. It is believed that this gene product interacts with RECQL4 protein via SMAD4 proteins, explaining the partial clinical overlap between PN and RTS. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Gene Name: Chromosome 16 open reading frame 57

Alternative Symbols: PN, Mpn1, HVSL1, hUsb1, C16orf57

Protein Name: Putative U6 snRNA phosphodiesterase

Molekulargewicht: 29kDa

Gen-ID: 79650

NCBI Accession: NP_078874

UniProt: Q9BQ65