NPLOC4 Antikörper (N-Term)
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- Target Alle NPLOC4 Antikörper anzeigen
- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
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Bindungsspezifität
- N-Term
- Reaktivität
- Human, Maus, Ratte, Pferd, Kaninchen, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Meerschweinchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser NPLOC4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GLKAFGAPNV VEDEIDQYLS KQDGKIYRSR DPQLCRHGPL GKCVHCVPLE
- Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against Nploc4. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Nploc4
- Top Product
- Discover our top product NPLOC4 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 608 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))
- Andere Bezeichnung
- Nploc4 (NPLOC4 Produkte)
- Synonyme
- NPL4 antikoerper, AK129375 antikoerper, Npl4 antikoerper, mKIAA1499 antikoerper, NPL4 homolog, ubiquitin recognition factor antikoerper, NPLOC4 antikoerper, Nploc4 antikoerper
- Hintergrund
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The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.
Alias Symbols: AK129375, Npl4, mKIAA1499
Protein Interaction Partner: Map3k1, Vcp, Ubc, Itpr1,
Protein Size: 608 - Molekulargewicht
- 66 kDa
- Gen-ID
- 217365
- NCBI Accession
- NM_001195023, NP_001181952
- UniProt
- P60670
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