RASAL1 Antikörper (C-Term)

Produktnummer ABIN2789073

Der Kaninchen Polyklonal anti-RASAL1 Antikörper wird verwendet zum Nachweis von RASAL1 in Proben von Human und Schwein. Er wurde validiert für WB.

Kurzübersicht für RASAL1 Antikörper (C-Term) (ABIN2789073)

Target: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Reaktivität: Human, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASAL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RASAL1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: RASAL1 Antibody - C-terminal region

Sequenz: DTTLEADTGA CPEVLARQRA ATARLLEVLA DLDRAHEEFQ QQERGKAALG

Homologie: Human: 100%, Pig: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against RASAL1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62227-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu RASAL1

Target: RASAL1 (RAS Protein Activator Like 1 (GAP1 Like) (RASAL1))

Andere Bezeichnung: RASAL1

Hintergrund:

Background Information: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described.

Gene Name: RAS protein activator like 1 (GAP1 like)

Alternative Symbols: RASAL

Protein Name: RasGAP-activating-like protein 1

Molekulargewicht: 88kDa

Gen-ID: 8437

NCBI Accession: NP_004649

UniProt: O95294