ORC3 Antikörper (N-Term)

Produktnummer ABIN2789072

Produktdetails anti-ORC3 Antikörper

Target: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Rind (Kuh), Hund, Ratte, Schwein, Kaninchen, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ORC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RFETYQLIWQ QMKSENERLQ EELNKNLFDN LIEFLQKSHS GFQKNSRDLG

Homologie: Cow: 93%, Dog: 93%, Human: 100%, Mouse: 79%, Pig: 90%, Rabbit: 93%, Rat: 83%, Yeast: 90%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against ORC3L. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 712 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ORC3

Target: ORC3 (Origin Recognition Complex, Subunit 3 (ORC3))

Andere Bezeichnung: ORC3L (ORC3 Produkte)

Synonyme: CG4088 antikoerper, DmORC3 antikoerper, DmOrc3 antikoerper, Dmel\\CG4088 antikoerper, LAT antikoerper, ORC antikoerper, ORC3 antikoerper, Orc3 antikoerper, l(2)49Fd antikoerper, l(2)vr6 antikoerper, vr-6 antikoerper, vr6 antikoerper, ORC3L antikoerper, orc3 antikoerper, ATORC3 antikoerper, F5E19.30 antikoerper, F5E19_30 antikoerper, ORIGIN RECOGNITION COMPLEX SUBUNIT 3 antikoerper, origin recognition complex subunit 3 antikoerper, Afu8g04240 antikoerper, DDBDRAFT_0216767 antikoerper, DDBDRAFT_0233773 antikoerper, DDB_0216767 antikoerper, DDB_0233773 antikoerper, LOC100226325 antikoerper, LATHEO antikoerper, Orc3l antikoerper, Origin recognition complex subunit 3 antikoerper, origin recognition complex subunit 3 antikoerper, origin recognition complex, subunit 3 antikoerper, Orc3 antikoerper, ORC3 antikoerper, orc3 antikoerper, AFUA_8G04240 antikoerper, BDBG_01002 antikoerper, orcC antikoerper

Hintergrund: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Studies of a similar gene in Drosophila suggested a possible role of this protein in neuronal proliferation and olfactory memory. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene.
Alias Symbols: LAT, LATHEO, ORC3, ORC3L
Protein Interaction Partner: ORC5, ORC4, ORC1, MCM7, CDC6, MCM10, ORC6, CCNE2, CDC45, LRWD1, ORC2, APP, SUMO2, XRCC5, UBC, XRCC6, ZBP1, DBF4, ORC3, MCM5, CDK4, TERF2, BRCA1, MCM4,
Protein Size: 712

Molekulargewicht: 82 kDa

Gen-ID: 23595

NCBI Accession: NM_181837, NP_862820

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Feeding Behaviour, Synthesis of DNA