HRH3 Antikörper (N-Term)

Produktnummer ABIN2789052

Der Kaninchen Polyklonal anti-HRH3 Antikörper wird verwendet zum Nachweis von HRH3 in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Hund und Kaninchen. Er wurde validiert für WB.

Kurzübersicht für HRH3 Antikörper (N-Term) (ABIN2789052)

Target: HRH3 (Histamine Receptor H3 (HRH3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRH3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HRH3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: Hrh3 Antibody - N-terminal region

Sequenz: VFNIVLISYD RFLSVTRAVS YRAQQGDTRR AVRKMALVWV LAFLLYGPAI

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Hrh3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Hrh3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP62180-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu HRH3

Target: HRH3 (Histamine Receptor H3 (HRH3))

Andere Bezeichnung: Hrh3

Hintergrund:

Background Information: This gene encodes a histamine H3 receptor that belongs to the superfamily of G-protein coupled receptors. This protein functions as a presynaptic autoreceptor on histamine neurons in the brain, and a presynaptic heteroreceptor in nonhistamine-containing neurons in both the central and peripheral nervous systems. It is deemed a great target for the development of therapeutics for numerous disorders, including obesity, epilepsy, and such cognitive diseases as attention deficit hyperactivity disorder and Alzheimer's disease. Several alternatively spliced transcript variants encoding different isoforms, with different brain expression patterns and signaling properties, have been described for this gene.

Gene Name: histamine receptor H3

Alternative Symbols: -

Protein Name: Histamine H3 receptor

Molekulargewicht: 48kDa

Gen-ID: 85268

NCBI Accession: NP_445958

UniProt: Q9QYN8

Pathways: cAMP Metabolic Process, Feeding Behaviour