BAG5 Antikörper (C-Term)

Produktnummer ABIN2788981

Dieses Anti-BAG5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BAG5 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen und Schwein. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für BAG5 Antikörper (C-Term) (ABIN2788981)

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAG5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BAG5 Antikörper

Bindungsspezifität: C-Term

Sequenz: LEKRKLFACE EHPSHKAVWN VLGNLSEIQG EVLSFDGNRT DKNYIRLEEL

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against BAG5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 488 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-BAG5 Antikörper (ABIN2788981)

Yue, Zhao, Huang, Li, Zhu, Feng, Hu: "A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis." in: Cell discovery, Vol. 2, pp. 16039, (2016) (PubMed).

Details zu BAG5

Target: BAG5 (BCL2-Associated Athanogene 5 (BAG5))

Andere Bezeichnung: BAG5

Hintergrund: The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene.
Alias Symbols: BAG-5
Protein Interaction Partner: CCDC155, FAM118B, THAP1, BANP, MAD1L1, TP53, TRIM27, FAM96B, MAD2L1, DLG5, UBC, LATS2, SOX2, MMS19, CIRBP, LRRK2, CUL3, FBXO25, PARK2, HSPA4, SNCA, STUB1, OTUD4, UIMC1, BAG5,
Protein Size: 488

Molekulargewicht: 56 kDa

Gen-ID: 9529

NCBI Accession: NM_001015049, NP_001015049

Pathways: SARS-CoV-2 Protein Interaktom