EIF3F Antikörper (C-Term)

Produktnummer ABIN2788968

Dieses Anti-EIF3F-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EIF3F in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für EIF3F Antikörper (C-Term) (ABIN2788968)

Target: EIF3F (Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF3F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EIF3F Antikörper

Bindungsspezifität: C-Term

Sequenz: IQDALSTVLQ YAEDVLSGKV SADNTVGRFL MSLVNQVPKI VPDDFETMLN

Homologie: Cow: 100%, Dog: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF3F. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 357 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF3F

Target: EIF3F (Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))

Andere Bezeichnung: EIF3F

Hintergrund: EIF3F is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Alias Symbols: EIF3S5, eIF3-p47
Protein Interaction Partner: HUWE1, UBC, SUMO2, RNF2, FBXO6, RPS6KB1, IGSF8, ICAM1, CD81, DDX3X, gag-pol, EIF3D, EIF3B, ATXN1, SMAD9, FN1, EIF3M, EIF3C, EIF3A, MSMO1, EIF3E, ATP6V1A, APP, EIF3L, EIF3K, MRPL46, EIF3I, EIF3H, EIF3G, UBD, HNRNPK, CDK11B, YWHAZ, NOTCH1, DTX1, RAD21, FBXO
Protein Size: 357

Molekulargewicht: 39 kDa

Gen-ID: 8665

NCBI Accession: NM_003754, NP_003745

UniProt: O00303

Pathways: Ribonucleoprotein Complex Subunit Organization