EIF3F Antikörper (N-Term)

Produktnummer ABIN2788967

Der Kaninchen Polyklonal Anti-EIF3F-Antikörper wurde für WB validiert. Er ist geeignet, EIF3F in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Zebrafisch (Danio rerio) und Meerschweinchen zu detektieren.

Kurzübersicht für EIF3F Antikörper (N-Term) (ABIN2788967)

Target: EIF3F (Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Pferd, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF3F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EIF3F Antikörper

Bindungsspezifität: N-Term

Sequenz: VILASIVDSY ERRNEGAARV IGTLLGTVDK HSVEVTNCFS VPHNESEDEV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF3F. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 357 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF3F

Target: EIF3F (Eukaryotic Translation Initiation Factor 3 Subunit F (EIF3F))

Andere Bezeichnung: EIF3F

Hintergrund: EIF3F is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Alias Symbols: EIF3S5, eIF3-p47
Protein Interaction Partner: HUWE1, UBC, SUMO2, RNF2, FBXO6, RPS6KB1, IGSF8, ICAM1, CD81, DDX3X, gag-pol, EIF3D, EIF3B, ATXN1, SMAD9, FN1, EIF3M, EIF3C, EIF3A, MSMO1, EIF3E, ATP6V1A, APP, EIF3L, EIF3K, MRPL46, EIF3I, EIF3H, EIF3G, UBD, HNRNPK, CDK11B, YWHAZ, NOTCH1, DTX1, RAD21, FBXO
Protein Size: 357

Molekulargewicht: 39 kDa

Gen-ID: 8665

NCBI Accession: NM_003754, NP_003745

UniProt: O00303

Pathways: Ribonucleoprotein Complex Subunit Organization