ARFGAP3 Antikörper (C-Term)

Produktnummer ABIN2788930

Dieses Anti-ARFGAP3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ARFGAP3 in WB. Geeignet für Human, Ratte, Hund, Rind (Kuh), Pferd und Schwein.

Kurzübersicht für ARFGAP3 Antikörper (C-Term) (ABIN2788930)

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Reaktivität: Human, Ratte, Hund, Rind (Kuh), Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ARFGAP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ARFGAP3 Antikörper

Bindungsspezifität: C-Term

Sequenz: SYWKKETSKD TETVLKTTGY SDRPTARRKP DYEPVENTDE AQKKFGNVKA

Homologie: Cow: 86%, Dog: 100%, Horse: 93%, Human: 100%, Pig: 79%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against ARFGAP3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 516 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ARFGAP3

Target: ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))

Andere Bezeichnung: ARFGAP3

Hintergrund: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
Alias Symbols: ARFGAP1, FLJ45618
Protein Interaction Partner: UBC, CXCL8, CD14, APP, SMAD2,
Protein Size: 516

Molekulargewicht: 57 kDa

Gen-ID: 26286

NCBI Accession: NM_014570, NP_055385

UniProt: Q9NP61