VNN2 Antikörper (C-Term)

Produktnummer ABIN2788913

Produktdetails anti-VNN2 Antikörper

Target: VNN2 (Vanin 2 (VNN2))

Bindungsspezifität: C-Term

Reaktivität: Human, Rind (Kuh), Pferd, Hund, Schwein, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser VNN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FRGFISRDGF NFTELFENAG NLTVCQKELC CHLSYRMLQK EENEVYVLGA

Homologie: Cow: 79%, Dog: 89%, Horse: 86%, Human: 100%, Pig: 93%, Sheep: 86%, Zebrafish: 75%

Produktmerkmale: This is a rabbit polyclonal antibody against VNN2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 520 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu VNN2

Target: VNN2 (Vanin 2 (VNN2))

Andere Bezeichnung: VNN2 (VNN2 Produkte)

Hintergrund: This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: FOAP-4, GPI-80
Protein Interaction Partner: ITGB2,
Protein Size: 520

Molekulargewicht: 57 kDa

Gen-ID: 8875

NCBI Accession: NM_004665, NP_004656

UniProt: O95498