Dematin Antikörper (Middle Region)

Produktnummer ABIN2788873

Produktdetails anti-Dematin Antikörper

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dematin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KKPPIYKQRE SVGGSPQTKH LIEDLIIESS KFPAAQPPDP NQPAKIETDY

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 85%, Human: 100%, Mouse: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EPB49. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 405 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Dematin

Target: Dematin (EPB49) (erythrocyte Membrane Protein Band 4.9 (Dematin) (EPB49))

Andere Bezeichnung: EPB49 (EPB49 Produkte)

Synonyme: MGC80597 antikoerper, MGC108072 antikoerper, EPB49 antikoerper, DMT antikoerper, AI325486 antikoerper, Epb4.9 antikoerper, Epb49 antikoerper, dematin antikoerper, dematin actin binding protein L homeolog antikoerper, dematin actin binding protein antikoerper, dmtn.L antikoerper, DMTN antikoerper, dmtn antikoerper, Dmtn antikoerper

Hintergrund: Dematin, or EPB49, is an actin-bundling protein originally identified in the erythroid membrane skeleton. Its actin-bundling activity is abolished upon phosphorylation by cAMP-dependent protein kinase and is restored after dephosphorylation.
Alias Symbols: DMT, FLJ78462, FLJ98848, EPB49
Protein Interaction Partner: GOLGA2, YWHAB, APP, NEDD4L, SNCA, PTOV1, DYNC1LI2, PRKACA, SNRPD2, PROCR, SPTB, EPB42, ACTB, ACTC1, DISC1,
Protein Size: 405

Molekulargewicht: 45 kDa

Gen-ID: 2039

NCBI Accession: NM_001978, NP_001969

UniProt: Q08495

Pathways: Regulation of Actin Filament Polymerization