EIF3A Antikörper (C-Term)

Produktnummer ABIN2788872

Produktdetails anti-EIF3A Antikörper

Target: EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF3A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PPALSRDRER DRDREREGEK EKASWRAEKD RESLRRTKNE TDEDGWTTVR

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF3A. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1382 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EIF3A

Target: EIF3A (Eukaryotic Translation Initiation Factor 3 Subunit A (EIF3A))

Andere Bezeichnung: EIF3A (EIF3A Produkte)

Synonyme: EIF3 antikoerper, EIF3S10 antikoerper, P167 antikoerper, TIF32 antikoerper, eIF3-p170 antikoerper, eIF3-theta antikoerper, p180 antikoerper, p185 antikoerper, EIF6 antikoerper, A830012B05Rik antikoerper, Csma antikoerper, Eif3 antikoerper, Eif3s10 antikoerper, mKIAA0139 antikoerper, ZH12 antikoerper, eif3s10 antikoerper, eIF3 p110 antikoerper, eIF3a antikoerper, eukaryotic translation initiation factor 3 subunit A antikoerper, eukaryotic translation initiation factor 3, subunit A antikoerper, eukaryotic translation initiation factor 3 subunit A S homeolog antikoerper, translation initiation factor eIF3a antikoerper, EIF3A antikoerper, Eif3a antikoerper, eif3a.S antikoerper, tif32 antikoerper

Hintergrund: EIF3A is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Alias Symbols: EIF3, EIF3S10, KIAA0139, P167, TIF32, eIF3-p170, eIF3-theta, p180, p185
Protein Interaction Partner: UBC, REL, TFIP11, WWP2, SUMO2, STAU1, LGR4, WWOX, EED, SHFM1, RNF2, EIF3CL, YTHDF2, LARP1, NUDT21, EIF3C, DYNC1I2, RPS26, RPS25, RPS23, RPS20, RPS18, RPS12, RPS10, RPS9, RPS3A, RPS3, FBXO6, TARDBP, EIF3D, UBD, ICAM1, CD81, RIOK2, IGSF8, BBS4, BBS1, gag-po
Protein Size: 1382

Molekulargewicht: 152 kDa

Gen-ID: 8661

NCBI Accession: NM_003750, NP_003741

UniProt: Q14152

Pathways: Ribonucleoprotein Complex Subunit Organization