SCARB2 Antikörper (C-Term)

Produktnummer ABIN2788868

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch SCARB2 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für SCARB2 Antikörper (C-Term) (ABIN2788868)

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SCARB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SCARB2 Antikörper

Bindungsspezifität: C-Term

Sequenz: KSMINTTLII TNIPYIIMAL GVFFGLVFTW LACKGQGSMD EGTADERAPL

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against SCARB2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SCARB2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SCARB2

Target: SCARB2 (Scavenger Receptor Class B, Member 2 (SCARB2))

Andere Bezeichnung: SCARB2

Hintergrund: The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF).
Alias Symbols: AMRF, CD36L2, EPM4, HLGP85, LGP85, LIMP-2, LIMPII, SR-BII
Protein Interaction Partner: UBC, ATP4A, TAF15, NONO, HSPD1, DDX1, ATP6V1B1, Ap1g1, AP3S2, AP3S1, THBS1,
Protein Size: 478

Molekulargewicht: 50 kDa

Gen-ID: 950

NCBI Accession: NM_005506, NP_005497

UniProt: Q14108