GIT2 Antikörper (C-Term)

Produktnummer ABIN2788863

Dieses Anti-GIT2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von GIT2 in WB. Geeignet für Human, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Meerschweinchen und Kaninchen.

Kurzübersicht für GIT2 Antikörper (C-Term) (ABIN2788863)

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Reaktivität: Human, Ratte, Hund, Rind (Kuh), Pferd, Schwein, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GIT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GIT2 Antikörper

Bindungsspezifität: C-Term

Sequenz: VQTGSEYTDT SNHSSLKRRP SARGSRPMSM YETGSGQKPY LPMGEASRPE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Pig: 100%, Rabbit: 93%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against GIT2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 759 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GIT2

Target: GIT2 (G Protein-Coupled Receptor Kinase Interactor 2 (GIT2))

Andere Bezeichnung: GIT2

Hintergrund: This gene encodes a member of the GIT protein family, which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity. GIT proteins traffic between cytoplasmic complexes, focal adhesions, and the cell periphery, and interact with Pak interacting exchange factor beta (PIX) to form large oligomeric complexes that transiently recruit other proteins. GIT proteins regulate cytoskeletal dynamics and participate in receptor internalization and membrane trafficking. This gene has been shown to repress lamellipodial extension and focal adhesion turnover, and is thought to regulate cell motility. This gene undergoes extensive alternative splicing to generate multiple isoforms, but the full-length nature of some of these variants has not been determined.
Alias Symbols: CAT-2, DKFZp686G01261, KIAA0148, MGC760, CAT2
Protein Interaction Partner: UBC, QPRT, ATF5, CORO1A, HNRNPUL1, TNIP1, CALCOCO2, MVP, RUSC2, SAFB2, IKBKG, SPOP, TSN, TRAF1, TNFAIP3, RCVRN, PROX1, NME2, NFKBIB, SMAD3, LMNB1, KRT18, HGD, GUSB, GCH1, E2F2, C4BPA, ACTN1, ACTG1, Dlg4, POLR1B, USHBP1, RUFY1, SH3GLB2, KCTD5, UBQLN1, EDC4
Protein Size: 759

Molekulargewicht: 83 kDa

Gen-ID: 9815

NCBI Accession: NM_057169, NP_476510

UniProt: Q14161

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling