RPL7 Antikörper (N-Term)

Produktnummer ABIN2788853

Der Kaninchen Polyklonal Anti-RPL7-Antikörper wurde für WB validiert. Er ist geeignet, RPL7 in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen und Kaninchen zu detektieren.

Kurzübersicht für RPL7 Antikörper (N-Term) (ABIN2788853)

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPL7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RPL7 Antikörper

Bindungsspezifität: N-Term

Sequenz: KKKRRNFAEL KIKRLRKKFA QKMLRKARRK LIYEKAKHYH KEYRQMYRTE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RPL7. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 248 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RPL7

Target: RPL7 (Ribosomal Protein L7 (RPL7))

Andere Bezeichnung: RPL7

Hintergrund: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: MGC117326, humL7-1, L7
Protein Interaction Partner: UBC, SUMO2, TUBGCP4, CEP250, TUBG1, TP53, STAU1, MDM2, LGR4, RPA3, RPA2, RPA1, RNF2, EED, PARK2, TARDBP, YWHAQ, PAN2, PHB, HSP90AB1, HSP90AA1, NOS2, IPO5, IL7R, FN1, ESR1, VCAM1, UBL4A, RAN, TRAF3IP1, EIF4A3, PPP1CC, MAGOH, HSP90AA5P, RPLP0P6, RPL10L, NIF
Protein Size: 248

Molekulargewicht: 29 kDa

Gen-ID: 6129

NCBI Accession: NM_000971, NP_000962

UniProt: P18124