SURF1 Antikörper (N-Term)

Produktnummer ABIN2788832

Der Kaninchen Polyklonal anti-SURF1 Antikörper wird verwendet zum Nachweis von SURF1 in Proben von Human, Rind (Kuh), Meerschweinchen und Pferd. Er wurde validiert für WB.

Kurzübersicht für SURF1 Antikörper (N-Term) (ABIN2788832)

Target: SURF1 (Surfeit 1 (SURF1))

Reaktivität: Human, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SURF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SURF1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: SURF1 Antibody - N-terminal region

Sequenz: GLRAAGLGRA PASAAWRSVL RVSPRPGVAW RPSRCGSSAA EASATKAEDD

Homologie: Cow: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SURF1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61537-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu SURF1

Target: SURF1 (Surfeit 1 (SURF1))

Andere Bezeichnung: SURF1

Hintergrund:

Background Information: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.

Gene Name: Surfeit 1

Alternative Symbols: SHY1, CMT4K, MC4DN1

Protein Name: Surfeit locus protein 1

Molekulargewicht: 33kDa

Gen-ID: 6834

NCBI Accession: NP_003163

UniProt: Q15526

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process