SURF1 Antikörper (N-Term)

Produktnummer ABIN2788832

Der Kaninchen Polyklonal Anti-SURF1-Antikörper wurde für WB validiert. Er ist geeignet, SURF1 in Proben von Human, Rind (Kuh), Meerschweinchen und Pferd zu detektieren.

Kurzübersicht für SURF1 Antikörper (N-Term) (ABIN2788832)

Target: SURF1 (Surfeit 1 (SURF1))

Reaktivität: Human, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SURF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SURF1 Antikörper

Bindungsspezifität: N-Term

Sequenz: GLRAAGLGRA PASAAWRSVL RVSPRPGVAW RPSRCGSSAA EASATKAEDD

Homologie: Cow: 79%, Guinea Pig: 86%, Horse: 86%, Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SURF1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 300 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SURF1

Target: SURF1 (Surfeit 1 (SURF1))

Andere Bezeichnung: SURF1

Hintergrund: This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency.
Alias Symbols: -
Protein Interaction Partner: UBC, PTGES3, CHCHD4, SFXN3, NDUFA12, NDUFAF3, SAMM50, FKBP8, UQCRC1, SRSF5, ABCD3, NDUFV2, NDUFS8, NDUFS3, NDUFB8, ABCC1, CYC1, COX15,
Protein Size: 300

Molekulargewicht: 33 kDa

Gen-ID: 6834

NCBI Accession: NM_003172, NP_003163

UniProt: Q15526

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process