Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PDLIM7 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio).
PDLIM7
Reaktivität: Human
WB, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeat freeze-thaw cycles.
Lagerung
-20 °C
Informationen zur Lagerung
For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target
PDLIM7
(PDZ and LIM Domain 7 (Enigma) (PDLIM7))
Andere Bezeichnung
PDLIM7
Hintergrund
The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants. Protein Interaction Partner: WWP2, IQGAP1, TSG101, PHF1, DGCR6, BAG3, RET, CBLC, COPS5, PARP1, YAP1, HNRNPD, PRKD2, ZMYND11, TRADD, UBC, SH3BP2, MYC, Hoxa1, NDUFA7, PCBP1, UBQLN4, TRAF3, TRAF2, TAB2, TRAF6, NR2C2, SMURF1, TP53, MDM2, Cdk1, PSMF1, SH2B2, C20orf195, AP5B1, ENKD1, TPM2, Protein Size: 287