LGI1 Antikörper (N-Term)

Produktnummer ABIN2788819

Der Kaninchen Polyklonal anti-LGI1 Antikörper (ABIN2788819) detektiert spezifisch LGI1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für LGI1 Antikörper (N-Term) (ABIN2788819)

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LGI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LGI1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: LGI1 Antibody - N-terminal region

Sequenz: LLSALLLTEG KKPAKPKCPA VCTCTKDNAL CENARSIPRT VPPDVISLSF

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against LGI1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP61478-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu LGI1

Target: LGI1 (Leucine-Rich, Glioma Inactivated 1 (LGI1))

Andere Bezeichnung: LGI1

Hintergrund:

Background Information: This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.

Gene Name: Leucine-rich, glioma inactivated 1

Alternative Symbols: EPT, ETL1, ADLTE, ADPAEF, ADPEAF, IB1099, EPITEMPIN

Protein Name: Leucine-rich glioma-inactivated protein 1

Molekulargewicht: 61kDa

Gen-ID: 9211

NCBI Accession: NP_005088

UniProt: O95970