NUP153 Antikörper (C-Term)

Produktnummer ABIN2788808

Produktdetails anti-NUP153 Antikörper

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Bindungsspezifität: C-Term

Reaktivität: Human, Ratte, Maus, Hund, Schwein, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP153 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PKCQPVFSFG NSEQTKDENS SKSTFSFSMT KPSEKESEQP AKATFAFGAQ

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against NUP153. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1475 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NUP153

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Andere Bezeichnung: NUP153 (NUP153 Produkte)

Hintergrund: Nuclear pore complexes are extremely elaborate structures that mediate the regulated movement of macromolecules between the nucleus and cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are pore complex-specific glycoproteins characterized by cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. The protein encoded by this gene has three distinct domains: a N-terminal region within which a pore targeting domain has been identified, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats.
Alias Symbols: HNUP153, N153
Protein Interaction Partner: UBC, HDAC11, LMNA, ESR1, PNPT1, DPY30, FIP1L1, NUP107, NUP54, NUP50, NCAPD2, PRKCSH, MEA1, EIF4B, EEF1B2, CSTF2, C1QBP, CUL3, SIRT7, RANBP2, CTNNB1, XPO7, SUMO2, SMAD3, SUMO1, MAPK3, MAPK1, Mki67, Kifc5b, MYC, KPNB1, tat, APC, USP20, USP11, TPR, SENP2, XP
Protein Size: 1475

Molekulargewicht: 162 kDa

Gen-ID: 9972

NCBI Accession: NM_005124, NP_005115

UniProt: P49790

Pathways: Protein targeting to Nucleus